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Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824

Overview of attention for article published in Biotechnology for Biofuels and Bioproducts, August 2013
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Title
Secretion and assembly of functional mini-cellulosomes from synthetic chromosomal operons in Clostridium acetobutylicum ATCC 824
Published in
Biotechnology for Biofuels and Bioproducts, August 2013
DOI 10.1186/1754-6834-6-117
Pubmed ID
Authors

Katalin Kovács, Benjamin J Willson, Katrin Schwarz, John T Heap, Adam Jackson, David N Bolam, Klaus Winzer, Nigel P Minton

Abstract

Consolidated bioprocessing (CBP) is reliant on the simultaneous enzyme production, saccharification of biomass, and fermentation of released sugars into valuable products such as butanol. Clostridial species that produce butanol are, however, unable to grow on crystalline cellulose. In contrast, those saccharolytic species that produce predominantly ethanol, such as Clostridium thermocellum and Clostridium cellulolyticum, degrade crystalline cellulose with high efficiency due to their possession of a multienzyme complex termed the cellulosome. This has led to studies directed at endowing butanol-producing species with the genetic potential to produce a cellulosome, albeit by localising the necessary transgenes to unstable autonomous plasmids. Here we have explored the potential of our previously described Allele-Coupled Exchange (ACE) technology for creating strains of the butanol producing species Clostridium acetobutylicum in which the genes encoding the various cellulosome components are stably integrated into the genome.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 93 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
Indonesia 1 1%
United States 1 1%
South Africa 1 1%
Unknown 88 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 30 32%
Researcher 14 15%
Student > Master 8 9%
Student > Bachelor 7 8%
Professor > Associate Professor 5 5%
Other 17 18%
Unknown 12 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 43 46%
Biochemistry, Genetics and Molecular Biology 16 17%
Immunology and Microbiology 4 4%
Engineering 4 4%
Chemical Engineering 3 3%
Other 11 12%
Unknown 12 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2013.
All research outputs
#20,656,820
of 25,374,917 outputs
Outputs from Biotechnology for Biofuels and Bioproducts
#1,285
of 1,578 outputs
Outputs of similar age
#159,144
of 210,085 outputs
Outputs of similar age from Biotechnology for Biofuels and Bioproducts
#16
of 18 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,578 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 10th percentile – i.e., 10% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 210,085 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.