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Isolation and molecular characterisation of Halicephalobus gingivalis in the brain of a horse in Piedmont, Italy

Overview of attention for article published in Parasites & Vectors, March 2017
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Title
Isolation and molecular characterisation of Halicephalobus gingivalis in the brain of a horse in Piedmont, Italy
Published in
Parasites & Vectors, March 2017
DOI 10.1186/s13071-017-2070-3
Pubmed ID
Authors

Maria Domenica Pintore, Francesco Cerutti, Antonio D’Angelo, Cristiano Corona, Paola Gazzuola, Loretta Masoero, Corrado Colombo, Roberto Bona, Carlo Cantile, Simone Peletto, Cristina Casalone, Barbara Iulini

Abstract

A fatal case of meningoencephalitis was reported in a 13-year-old Koninklijk Warmbloed Paard Nederland stallion, suspected of West Nile virus (WNV) infection, in the Piedmont region of Italy. Clinical signs included right head tilt and circling, depression alternated with excitability, fever and lateral strabismus. Combined treatment consisting of dimethylsulfoxide, dexamethasone, sulphonamides and sedative was administered, but because of the poor conditions the horse was euthanatized and submitted for necropsy. At post-mortem examination no skin lesions were observed, all organs appeared normal on gross evaluation and only head and blood samples were further investigated. Neuropathological findings consisted of granulomatous meningoencephalitis and larvae and adult females of Halicephalobus gingivalis were isolated and identified from the digested brain. Frozen brain was submitted to PCR amplification and 220 bp multiple sequence alignment was analysed by Bayesian phylogenetic analysis. Phylogenetic inference revealed that the isolate belongs to H. gingivalis Lineage 3. WN surveillance can help to deepen our knowledge of horse neurological disorders investigating their causes and incidence. Moreover, it can help to understand the geographic distribution of the H. gingivalis, to unravel epidemiological information, and to estimate risk for humans.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 10%
Researcher 3 10%
Student > Ph. D. Student 3 10%
Lecturer > Senior Lecturer 2 7%
Student > Master 2 7%
Other 2 7%
Unknown 14 48%
Readers by discipline Count As %
Medicine and Dentistry 3 10%
Environmental Science 2 7%
Veterinary Science and Veterinary Medicine 2 7%
Immunology and Microbiology 2 7%
Agricultural and Biological Sciences 2 7%
Other 3 10%
Unknown 15 52%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 December 2017.
All research outputs
#17,881,664
of 22,958,253 outputs
Outputs from Parasites & Vectors
#3,838
of 5,484 outputs
Outputs of similar age
#221,363
of 307,995 outputs
Outputs of similar age from Parasites & Vectors
#112
of 163 outputs
Altmetric has tracked 22,958,253 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,484 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 307,995 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 163 others from the same source and published within six weeks on either side of this one. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.