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Modeling the within-host dynamics of HIV infection

Overview of attention for article published in BMC Biology, September 2013
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Title
Modeling the within-host dynamics of HIV infection
Published in
BMC Biology, September 2013
DOI 10.1186/1741-7007-11-96
Pubmed ID
Authors

Alan S Perelson, Ruy M Ribeiro

Abstract

The new field of viral dynamics, based on within-host modeling of viral infections, began with models of human immunodeficiency virus (HIV), but now includes many viral infections. Here we review developments in HIV modeling, emphasizing quantitative findings about HIV biology uncovered by studying acute infection, the response to drug therapy and the rate of generation of HIV variants that escape immune responses. We show how modeling has revealed many dynamical features of HIV infection and how it may provide insight into the ultimate cure for this infection.

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The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 260 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 2%
United Kingdom 1 <1%
India 1 <1%
South Africa 1 <1%
Unknown 252 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 58 22%
Researcher 47 18%
Student > Master 41 16%
Student > Doctoral Student 20 8%
Student > Bachelor 18 7%
Other 43 17%
Unknown 33 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 62 24%
Biochemistry, Genetics and Molecular Biology 27 10%
Mathematics 25 10%
Medicine and Dentistry 24 9%
Immunology and Microbiology 17 7%
Other 62 24%
Unknown 43 17%