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HIV interactions with monocytes and dendritic cells: viral latency and reservoirs

Overview of attention for article published in Retrovirology, June 2009
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Title
HIV interactions with monocytes and dendritic cells: viral latency and reservoirs
Published in
Retrovirology, June 2009
DOI 10.1186/1742-4690-6-51
Pubmed ID
Authors

Christopher M Coleman, Li Wu

Abstract

HIV is a devastating human pathogen that causes serious immunological diseases in humans around the world. The virus is able to remain latent in an infected host for many years, allowing for the long-term survival of the virus and inevitably prolonging the infection process. The location and mechanisms of HIV latency are under investigation and remain important topics in the study of viral pathogenesis. Given that HIV is a blood-borne pathogen, a number of cell types have been proposed to be the sites of latency, including resting memory CD4+ T cells, peripheral blood monocytes, dendritic cells and macrophages in the lymph nodes, and haematopoietic stem cells in the bone marrow. This review updates the latest advances in the study of HIV interactions with monocytes and dendritic cells, and highlights the potential role of these cells as viral reservoirs and the effects of the HIV-host-cell interactions on viral pathogenesis.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 246 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 6 2%
Portugal 2 <1%
South Africa 2 <1%
Brazil 1 <1%
Australia 1 <1%
Germany 1 <1%
Canada 1 <1%
United Kingdom 1 <1%
Spain 1 <1%
Other 1 <1%
Unknown 229 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 62 25%
Researcher 48 20%
Student > Master 32 13%
Student > Bachelor 28 11%
Student > Postgraduate 15 6%
Other 35 14%
Unknown 26 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 93 38%
Medicine and Dentistry 43 17%
Immunology and Microbiology 31 13%
Biochemistry, Genetics and Molecular Biology 25 10%
Chemistry 7 3%
Other 18 7%
Unknown 29 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 July 2018.
All research outputs
#22,778,604
of 25,394,764 outputs
Outputs from Retrovirology
#1,213
of 1,273 outputs
Outputs of similar age
#120,622
of 125,263 outputs
Outputs of similar age from Retrovirology
#10
of 10 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,273 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 125,263 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one.