Title |
Automatic registration of multi-modal microscopy images for integrative analysis of prostate tissue sections
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Published in |
BMC Cancer, September 2013
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DOI | 10.1186/1471-2407-13-408 |
Pubmed ID | |
Authors |
Giuseppe Lippolis, Anders Edsjö, Leszek Helczynski, Anders Bjartell, Niels Chr Overgaard |
Abstract |
Prostate cancer is one of the leading causes of cancer related deaths. For diagnosis, predicting the outcome of the disease, and for assessing potential new biomarkers, pathologists and researchers routinely analyze histological samples. Morphological and molecular information may be integrated by aligning microscopic histological images in a multiplex fashion. This process is usually time-consuming and results in intra- and inter-user variability. The aim of this study is to investigate the feasibility of using modern image analysis methods for automated alignment of microscopic images from differently stained adjacent paraffin sections from prostatic tissue specimens. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 4% |
United States | 1 | 2% |
Austria | 1 | 2% |
Unknown | 46 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 26% |
Student > Master | 8 | 16% |
Researcher | 8 | 16% |
Student > Bachelor | 5 | 10% |
Student > Doctoral Student | 2 | 4% |
Other | 6 | 12% |
Unknown | 8 | 16% |
Readers by discipline | Count | As % |
---|---|---|
Engineering | 11 | 22% |
Computer Science | 8 | 16% |
Agricultural and Biological Sciences | 6 | 12% |
Medicine and Dentistry | 6 | 12% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Other | 5 | 10% |
Unknown | 11 | 22% |