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Kinin B1 Receptors Contributes to Acute Pain following Minor Surgery in Humans

Overview of attention for article published in Molecular Pain, January 2010
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Title
Kinin B1 Receptors Contributes to Acute Pain following Minor Surgery in Humans
Published in
Molecular Pain, January 2010
DOI 10.1186/1744-8069-6-12
Pubmed ID
Authors

May Hamza, Xiao-Min Wang, Albert Adam, Jaime S Brahim, Janet S Rowan, Gilberto N Carmona, Raymond A Dionne

Abstract

Kinins play an important role in regulation of pain and hyperalgesia after tissue injury and inflammation by activating two types of G-protein-coupled receptors, the kinin B1 and B2 receptors. It is generally accepted that the B2 receptor is constitutively expressed, whereas the B1 receptor is induced in response to inflammation. However, little is known about the regulatory effects of kinin receptors on the onset of acute inflammation and inflammatory pain in humans. The present study investigated the changes in gene expression of kinin receptors and the levels of their endogenous ligands at an early time point following tissue injury and their relation to clinical pain, as well as the effect of COX-inhibition on their expression levels.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 19%
Student > Master 5 14%
Researcher 4 11%
Student > Doctoral Student 3 8%
Student > Ph. D. Student 3 8%
Other 5 14%
Unknown 9 25%
Readers by discipline Count As %
Medicine and Dentistry 13 36%
Agricultural and Biological Sciences 6 17%
Psychology 2 6%
Immunology and Microbiology 2 6%
Neuroscience 2 6%
Other 1 3%
Unknown 10 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2013.
All research outputs
#22,759,802
of 25,374,917 outputs
Outputs from Molecular Pain
#595
of 669 outputs
Outputs of similar age
#166,053
of 172,634 outputs
Outputs of similar age from Molecular Pain
#29
of 30 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 172,634 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 30 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.