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Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells

Overview of attention for article published in BMC Cancer, September 2013
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2 X users
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1 Facebook page

Citations

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24 Dimensions

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51 Mendeley
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Title
Stromal matrix metalloprotease-13 knockout alters Collagen I structure at the tumor-host interface and increases lung metastasis of C57BL/6 syngeneic E0771 mammary tumor cells
Published in
BMC Cancer, September 2013
DOI 10.1186/1471-2407-13-411
Pubmed ID
Authors

Seth W Perry, Jill M Schueckler, Kathleen Burke, Giuseppe L Arcuri, Edward B Brown

Abstract

Matrix metalloproteases and collagen are key participants in breast cancer, but their precise roles in cancer etiology and progression remain unclear. MMP13 helps regulate collagen structure and has been ascribed largely harmful roles in cancer, but some studies demonstrate that MMP13 may also protect against tumor pathology. Other studies indicate that collagen's organizational patterns at the breast tumor-host interface influence metastatic potential. Therefore we investigated how MMP13 modulates collagen I, a principal collagen subtype in breast tissue, and affects tumor pathology and metastasis in a mouse model of breast cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Poland 1 2%
Canada 1 2%
Unknown 48 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 33%
Researcher 9 18%
Student > Bachelor 4 8%
Other 4 8%
Professor 3 6%
Other 7 14%
Unknown 7 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 25%
Biochemistry, Genetics and Molecular Biology 10 20%
Medicine and Dentistry 6 12%
Engineering 6 12%
Immunology and Microbiology 2 4%
Other 4 8%
Unknown 10 20%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 January 2014.
All research outputs
#14,759,250
of 22,719,618 outputs
Outputs from BMC Cancer
#3,667
of 8,267 outputs
Outputs of similar age
#116,533
of 196,918 outputs
Outputs of similar age from BMC Cancer
#38
of 75 outputs
Altmetric has tracked 22,719,618 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,267 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,918 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.