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Elimination of Hepatitis B: Is It a Mission Possible?

Overview of attention for article published in BMC Medicine, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • Average Attention Score compared to outputs of the same age and source

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blogs
1 blog
twitter
5 X users
facebook
5 Facebook pages

Citations

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30 Dimensions

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51 Mendeley
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Title
Elimination of Hepatitis B: Is It a Mission Possible?
Published in
BMC Medicine, March 2017
DOI 10.1186/s12916-017-0820-x
Pubmed ID
Authors

Tai-Chung Tseng, Jia-Horng Kao

Abstract

Chronic hepatitis B virus (HBV) infection is a global public health issue. Although the disease cannot be cured effectively, disease management has been improved over the past decade. The introduction of potent nucleos(t)ide analogues (NAs) to suppress viral replication represented a giant leap in the control of this disease. It has been shown that tenofovir treatment, a potent NA, complements current immunoprophylaxis to diminish mother-to-infant transmission in pregnant women with a high viral load. For patients with chronic HBV infection, quantitative hepatitis B surface antigen is a useful tool to define inactive carriers and to guide antiviral therapy. Quantification of HBV mutants is also useful in predicting long-term outcomes more precisely than ever. The next challenge is how to achieve an HBV cure; although immunotherapy is a promising strategy, the current results from two clinical trials using therapeutic vaccines to induce HBV-specific immune response in patients with chronic HBV infection are disappointing. In the coming years, we are expecting to see a combination of therapeutic agents with various modes of action to complete the mission of HBV elimination.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 51 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 20%
Student > Bachelor 7 14%
Student > Doctoral Student 5 10%
Other 5 10%
Student > Master 5 10%
Other 10 20%
Unknown 9 18%
Readers by discipline Count As %
Medicine and Dentistry 12 24%
Biochemistry, Genetics and Molecular Biology 8 16%
Agricultural and Biological Sciences 8 16%
Nursing and Health Professions 4 8%
Pharmacology, Toxicology and Pharmaceutical Science 3 6%
Other 4 8%
Unknown 12 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2018.
All research outputs
#2,882,093
of 24,185,663 outputs
Outputs from BMC Medicine
#1,781
of 3,698 outputs
Outputs of similar age
#52,749
of 311,796 outputs
Outputs of similar age from BMC Medicine
#36
of 65 outputs
Altmetric has tracked 24,185,663 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,698 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 45.4. This one has gotten more attention than average, scoring higher than 51% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,796 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 65 others from the same source and published within six weeks on either side of this one. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.