Title |
Comparative genomics of emerging pathogens in the Candida glabrata clade
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Published in |
BMC Genomics, September 2013
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DOI | 10.1186/1471-2164-14-623 |
Pubmed ID | |
Authors |
Toni Gabaldón, Tiphaine Martin, Marina Marcet-Houben, Pascal Durrens, Monique Bolotin-Fukuhara, Olivier Lespinet, Sylvie Arnaise, Stéphanie Boisnard, Gabriela Aguileta, Ralitsa Atanasova, Christiane Bouchier, Arnaud Couloux, Sophie Creno, Jose Almeida Cruz, Hugo Devillers, Adela Enache-Angoulvant, Juliette Guitard, Laure Jaouen, Laurence Ma, Christian Marck, Cécile Neuvéglise, Eric Pelletier, Amélie Pinard, Julie Poulain, Julien Recoquillay, Eric Westhof, Patrick Wincker, Bernard Dujon, Christophe Hennequin, Cécile Fairhead |
Abstract |
Candida glabrata follows C. albicans as the second or third most prevalent cause of candidemia worldwide. These two pathogenic yeasts are distantly related, C. glabrata being part of the Nakaseomyces, a group more closely related to Saccharomyces cerevisiae. Although C. glabrata was thought to be the only pathogenic Nakaseomyces, two new pathogens have recently been described within this group: C. nivariensis and C. bracarensis. To gain insight into the genomic changes underlying the emergence of virulence, we sequenced the genomes of these two, and three other non-pathogenic Nakaseomyces, and compared them to other sequenced yeasts. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 2 | <1% |
United States | 2 | <1% |
Taiwan | 1 | <1% |
Ireland | 1 | <1% |
Sweden | 1 | <1% |
Poland | 1 | <1% |
Unknown | 198 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 48 | 23% |
Student > Master | 36 | 17% |
Researcher | 30 | 15% |
Student > Bachelor | 20 | 10% |
Student > Doctoral Student | 12 | 6% |
Other | 31 | 15% |
Unknown | 29 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 74 | 36% |
Biochemistry, Genetics and Molecular Biology | 51 | 25% |
Immunology and Microbiology | 17 | 8% |
Medicine and Dentistry | 8 | 4% |
Computer Science | 6 | 3% |
Other | 12 | 6% |
Unknown | 38 | 18% |