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Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy

Overview of attention for article published in Journal of Neuroinflammation, September 2013
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1 tweeter

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Title
Involvement of neuronal IL-1β in acquired brain lesions in a rat model of neonatal encephalopathy
Published in
Journal of Neuroinflammation, September 2013
DOI 10.1186/1742-2094-10-110
Pubmed ID
Authors

Alexandre Savard, Karine Lavoie, Marie-Elsa Brochu, Djordje Grbic, Martin Lepage, Denis Gris, Guillaume Sebire

Abstract

Infection-inflammation combined with hypoxia-ischemia (HI) is the most prevalent pathological scenario involved in perinatal brain damage leading to life-long neurological disabilities. Following lipopolysaccharide (LPS) and/or HI aggression, different patterns of inflammatory responses have been uncovered according to the brain differentiation stage. In fact, LPS pre-exposure has been reported to aggravate HI brain lesions in post-natal day 1 (P1) and P7 rat models that are respectively equivalent - in terms of brain development - to early and late human preterm newborns. However, little is known about the innate immune response in LPS plus HI-induced lesions of the full-term newborn forebrain and the associated neuropathological and neurobehavioral outcomes.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 57 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 32%
Researcher 10 18%
Student > Master 6 11%
Student > Bachelor 5 9%
Student > Doctoral Student 3 5%
Other 7 12%
Unknown 8 14%
Readers by discipline Count As %
Neuroscience 13 23%
Agricultural and Biological Sciences 10 18%
Medicine and Dentistry 9 16%
Biochemistry, Genetics and Molecular Biology 3 5%
Nursing and Health Professions 3 5%
Other 9 16%
Unknown 10 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2013.
All research outputs
#3,068,909
of 4,507,280 outputs
Outputs from Journal of Neuroinflammation
#452
of 659 outputs
Outputs of similar age
#66,312
of 97,753 outputs
Outputs of similar age from Journal of Neuroinflammation
#13
of 16 outputs
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So far Altmetric has tracked 659 research outputs from this source. They receive a mean Attention Score of 3.1. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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We're also able to compare this research output to 16 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.