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X Demographics
Mendeley readers
Attention Score in Context
| Title |
An update on the hyper-IgE syndromes
|
|---|---|
| Published in |
Arthritis Research & Therapy, November 2012
|
| DOI | 10.1186/ar4069 |
| Pubmed ID | |
| Authors |
Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher |
| Abstract |
ABSTRACT: The hyper-IgE syndromes (HIES; originally named Job's syndrome) are a collection of primary immunodeficiency syndromes resulting in elevated serum IgE levels and typified by recurrent staphylococcal skin abscesses, eczema and pulmonary infections. The disorder has autosomal dominant and recessive forms. Autosomal dominant HIES has been shown to be mainly due to STAT3 mutations and additionally results in connective tissue, skeletal, vascular and dental abnormalities. Autosomal recessive HIES has been shown to be mainly due to mutations in DOCK8; these patients are more prone to viral skin infections instead. This review article discusses the common clinical features of the syndrome, the genetic mutations responsible and the pathogenesis of the disease, as well as treatments currently used. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 126 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 126 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 16 | 13% |
| Researcher | 15 | 12% |
| Other | 13 | 10% |
| Student > Postgraduate | 13 | 10% |
| Student > Ph. D. Student | 12 | 10% |
| Other | 29 | 23% |
| Unknown | 28 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 67 | 53% |
| Immunology and Microbiology | 10 | 8% |
| Agricultural and Biological Sciences | 8 | 6% |
| Biochemistry, Genetics and Molecular Biology | 5 | 4% |
| Computer Science | 1 | <1% |
| Other | 6 | 5% |
| Unknown | 29 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 August 2017.
All research outputs
#15,169,543
of 25,374,647 outputs
Outputs from Arthritis Research & Therapy
#2,203
of 3,381 outputs
Outputs of similar age
#170,103
of 285,602 outputs
Outputs of similar age from Arthritis Research & Therapy
#26
of 47 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 285,602 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 47 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.