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Augmentation therapy for alpha-1 antitrypsin deficiency: towards a personalised approach

Overview of attention for article published in Orphanet Journal of Rare Diseases, September 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • High Attention Score compared to outputs of the same age and source (82nd percentile)

Mentioned by

news
1 news outlet
twitter
3 X users

Citations

dimensions_citation
72 Dimensions

Readers on

mendeley
68 Mendeley
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Title
Augmentation therapy for alpha-1 antitrypsin deficiency: towards a personalised approach
Published in
Orphanet Journal of Rare Diseases, September 2013
DOI 10.1186/1750-1172-8-149
Pubmed ID
Authors

Robert A Stockley, Marc Miravitlles, Claus Vogelmeier, Behalf of Alpha One International Registry (A.I.R.)

Abstract

Intravenous augmentation therapy is the only specific treatment available for emphysema associated with alpha-1 antitrypsin deficiency. Despite large observational studies and limited interventional studies there remains controversy about the efficacy of this treatment due to the impracticality of conducting adequately powered studies to evaluate the rate of decline in lung function, due to the low prevalence and the slow progression of the disease. However, measurement of lung density by computed tomography is a more specific and sensitive marker of the evolution of emphysema and two small placebo-controlled clinical trials have provided evidence supporting a reduction in the rate of decline in lung density with augmentation therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 3%
United Kingdom 1 1%
Spain 1 1%
Germany 1 1%
Unknown 63 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 16%
Student > Ph. D. Student 8 12%
Student > Bachelor 8 12%
Librarian 4 6%
Other 4 6%
Other 15 22%
Unknown 18 26%
Readers by discipline Count As %
Medicine and Dentistry 24 35%
Agricultural and Biological Sciences 8 12%
Biochemistry, Genetics and Molecular Biology 6 9%
Economics, Econometrics and Finance 3 4%
Business, Management and Accounting 2 3%
Other 5 7%
Unknown 20 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2023.
All research outputs
#4,659,861
of 25,374,917 outputs
Outputs from Orphanet Journal of Rare Diseases
#644
of 3,105 outputs
Outputs of similar age
#39,404
of 215,077 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#9
of 51 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,105 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 215,077 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.