Title |
Genome-wide signatures of differential DNA methylation in pediatric acute lymphoblastic leukemia
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Published in |
Genome Biology, September 2013
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DOI | 10.1186/gb-2013-14-9-r105 |
Pubmed ID | |
Authors |
Jessica Nordlund, Christofer L Bäcklin, Per Wahlberg, Stephan Busche, Eva C Berglund, Maija-Leena Eloranta, Trond Flaegstad, Erik Forestier, Britt-Marie Frost, Arja Harila-Saari, Mats Heyman, Ólafur G Jónsson, Rolf Larsson, Josefine Palle, Lars Rönnblom, Kjeld Schmiegelow, Daniel Sinnett, Stefan Söderhäll, Tomi Pastinen, Mats G Gustafsson, Gudmar Lönnerholm, Ann-Christine Syvänen |
Abstract |
Although aberrant DNA methylation has been observed previously in acute lymphoblastic leukemia (ALL), the patterns of differential methylation have not been comprehensively determined in all subtypes of ALL on a genome-wide scale. The relationship between DNA methylation, cytogenetic background, drug resistance and relapse in ALL is poorly understood. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Germany | 1 | <1% |
Switzerland | 1 | <1% |
Netherlands | 1 | <1% |
Norway | 1 | <1% |
Belgium | 1 | <1% |
Spain | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 218 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 65 | 29% |
Researcher | 42 | 19% |
Student > Master | 21 | 9% |
Student > Bachelor | 20 | 9% |
Student > Doctoral Student | 17 | 8% |
Other | 22 | 10% |
Unknown | 39 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 67 | 30% |
Biochemistry, Genetics and Molecular Biology | 47 | 21% |
Medicine and Dentistry | 29 | 13% |
Computer Science | 7 | 3% |
Nursing and Health Professions | 4 | 2% |
Other | 25 | 11% |
Unknown | 47 | 21% |