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Dysregulation of the complement cascade in the hSOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis

Overview of attention for article published in Journal of Neuroinflammation, September 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

news
1 news outlet
twitter
4 X users
patent
1 patent

Citations

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77 Dimensions

Readers on

mendeley
59 Mendeley
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Title
Dysregulation of the complement cascade in the hSOD1G93Atransgenic mouse model of amyotrophic lateral sclerosis
Published in
Journal of Neuroinflammation, September 2013
DOI 10.1186/1742-2094-10-119
Pubmed ID
Authors

John D Lee, Nur A Kamaruzaman, Jenny NT Fung, Stephen M Taylor, Bradley J Turner, Julie D Atkin, Trent M Woodruff, Peter G Noakes

Abstract

Components of the innate immune complement system have been implicated in the pathogenesis of amyotrophic lateral sclerosis (ALS); however, a comprehensive examination of complement expression in this disease has not been performed. This study therefore aimed to determine the expression of complement components (C1qB, C4, factor B, C3/C3b, C5 and CD88) and regulators (CD55 and CD59a) in the lumbar spinal cord of hSOD1(G93A) mice during defined disease stages.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Turkey 1 2%
France 1 2%
Canada 1 2%
Unknown 56 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 19%
Student > Master 8 14%
Student > Ph. D. Student 7 12%
Student > Bachelor 6 10%
Student > Postgraduate 3 5%
Other 12 20%
Unknown 12 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 24%
Neuroscience 11 19%
Medicine and Dentistry 6 10%
Biochemistry, Genetics and Molecular Biology 5 8%
Business, Management and Accounting 2 3%
Other 8 14%
Unknown 13 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 15. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 September 2023.
All research outputs
#2,251,417
of 24,417,958 outputs
Outputs from Journal of Neuroinflammation
#286
of 2,811 outputs
Outputs of similar age
#20,052
of 208,363 outputs
Outputs of similar age from Journal of Neuroinflammation
#2
of 19 outputs
Altmetric has tracked 24,417,958 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,811 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.3. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,363 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.