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Tissue sparing, behavioral recovery, supraspinal axonal sparing/regeneration following sub-acute glial transplantation in a model of spinal cord contusion

Overview of attention for article published in BMC Neuroscience, September 2013
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Title
Tissue sparing, behavioral recovery, supraspinal axonal sparing/regeneration following sub-acute glial transplantation in a model of spinal cord contusion
Published in
BMC Neuroscience, September 2013
DOI 10.1186/1471-2202-14-106
Pubmed ID
Authors

Helen R Barbour, Christine D Plant, Alan R Harvey, Giles W Plant

Abstract

It has been shown that olfactory ensheathing glia (OEG) and Schwann cell (SCs) transplantation are beneficial as cellular treatments for spinal cord injury (SCI), especially acute and sub-acute time points. In this study, we transplanted DsRED transduced adult OEG and SCs sub-acutely (14 days) following a T10 moderate spinal cord contusion injury in the rat. Behaviour was measured by open field (BBB) and horizontal ladder walking tests to ascertain improvements in locomotor function. Fluorogold staining was injected into the distal spinal cord to determine the extent of supraspinal and propriospinal axonal sparing/regeneration at 4 months post injection time point. The purpose of this study was to investigate if OEG and SCs cells injected sub acutely (14 days after injury) could: (i) improve behavioral outcomes, (ii) induce sparing/regeneration of propriospinal and supraspinal projections, and (iii) reduce tissue loss.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 2%
United States 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 23%
Student > Bachelor 9 20%
Student > Ph. D. Student 9 20%
Student > Master 5 11%
Other 4 9%
Other 6 14%
Unknown 1 2%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 27%
Medicine and Dentistry 8 18%
Neuroscience 8 18%
Psychology 3 7%
Biochemistry, Genetics and Molecular Biology 2 5%
Other 7 16%
Unknown 4 9%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 September 2013.
All research outputs
#10,994,835
of 12,372,276 outputs
Outputs from BMC Neuroscience
#821
of 993 outputs
Outputs of similar age
#135,473
of 160,241 outputs
Outputs of similar age from BMC Neuroscience
#5
of 8 outputs
Altmetric has tracked 12,372,276 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 993 research outputs from this source. They receive a mean Attention Score of 3.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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