Title |
A systematic approach to statistical analysis in dosimetry and patient-specific IMRT plan verification measurements
|
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Published in |
Radiation Oncology, September 2013
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DOI | 10.1186/1748-717x-8-225 |
Pubmed ID | |
Authors |
Songbing Qin, Miao Zhang, Sung Kim, Ting Chen, Leonard H Kim, Bruce G Haffty, Ning J Yue |
Abstract |
In the presence of random uncertainties, delivered radiation treatment doses in patient likely exhibit a statistical distribution. The expected dose and variance of this distribution are unknown and are most likely not equal to the planned value since the current treatment planning systems cannot exactly model and simulate treatment machine. Relevant clinical questions are 1) how to quantitatively estimate the expected delivered dose and extrapolate the expected dose to the treatment dose over a treatment course and 2) how to evaluate the treatment dose relative to the corresponding planned dose. This study is to present a systematic approach to address these questions and to apply this approach to patient-specific IMRT (PSIMRT) plan verifications. |
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