Title |
Oxidative stress and apoptosis in a pig model of brain death (BD) and living donation (LD)
|
---|---|
Published in |
Journal of Translational Medicine, October 2013
|
DOI | 10.1186/1479-5876-11-244 |
Pubmed ID | |
Authors |
Philipp Stiegler, Michael Sereinigg, Andreas Puntschart, Andrea Bradatsch, Thomas Seifert-Held, Iris Wiederstein-Grasser, Bettina Leber, Elke Stadelmeyer, Nadia Dandachi, Siglinde Zelzer, Florian Iberer, Vanessa Stadlbauer |
Abstract |
As organ shortage is increasing, the acceptance of marginal donors increases, which might result in poor organ function and patient survival. Mostly, organ damage is caused during brain death (BD), cold ischemic time (CIT) or after reperfusion due to oxidative stress or the induction of apoptosis. The aim of this study was to study a panel of genes involved in oxidative stress and apoptosis and compare these findings with immunohistochemistry from a BD and living donation (LD) pig model and after cold ischemia time (CIT). |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 42 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 17% |
Researcher | 6 | 14% |
Student > Bachelor | 5 | 12% |
Student > Master | 4 | 10% |
Student > Doctoral Student | 3 | 7% |
Other | 8 | 19% |
Unknown | 9 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 20 | 48% |
Agricultural and Biological Sciences | 5 | 12% |
Nursing and Health Professions | 2 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 3 | 7% |
Unknown | 10 | 24% |