Oral vancomycin desensitisation to treat Clostridium difficile infection in a vancomycin allergic patient

- Desensitisation is not permanent, as sensitization may recur once regular exposure to the drug is stopped. https://t.co/JSfwHcOMXx

- For patients with C. diff intolerant to oral vancomycin, there are many successful case series and case reports on vancomycin desensitization (which can utilize intravenous doses or oral administration). https://t.co/JSfwHcOMXx

- Oral vancomycin is contraindicated in those allergic to intravenous vancomycin, due to the risk of exposure causing anaphylaxis. https://t.co/JSfwHcOMXx

- It's known that oral vancomycin is poorly absorbed from the gut. - Reports have shown there is systemic absorption in patients with inflamed colonic mucosa. - And serum vancomycin levels could be detected. https://t.co/JSfwHcOMXx https://t.co/D0KzkG4lb