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Plant miRNAs found in human circulating system provide evidences of cross kingdom RNAi

Overview of attention for article published in BMC Genomics, March 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

twitter
25 X users
peer_reviews
1 peer review site
facebook
2 Facebook pages
reddit
1 Redditor

Citations

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53 Dimensions

Readers on

mendeley
84 Mendeley
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Title
Plant miRNAs found in human circulating system provide evidences of cross kingdom RNAi
Published in
BMC Genomics, March 2017
DOI 10.1186/s12864-017-3502-3
Pubmed ID
Authors

Yu-Chen Liu, Wen Liang Chen, Wei-Hsiang Kung, Hsien-Da Huang

Abstract

Emerging evidence indicates that plant miRNAs can present within human circulating system through dietary intake and regulate human gene expression. Hence we deduced that comestible plants miRNAs can be identified in the public available small RNA sequencing data sets. In this study, we identified abundant plant miRNAs sequences from 410 human plasma small RNA sequencing data sets. One particular plant miRNA miR2910, conserved in fruits and vegetables, was found to present in high relative amount in the plasma samples. This miRNA, with same 6mer and 7mer-A1 target seed sequences as hsa-miR-4259 and hsa-miR-4715-5p, was predicted to target human JAK-STAT signaling pathway gene SPRY4 and transcription regulation genes. Through analysis of public available plasma small RNA sequencing data, we found the supporting evidence for the plant miRNAs cross kingdom RNAi within human circulating system.

X Demographics

X Demographics

The data shown below were collected from the profiles of 25 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 84 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 1 1%
United States 1 1%
Unknown 82 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 17 20%
Researcher 14 17%
Student > Master 10 12%
Student > Bachelor 7 8%
Professor > Associate Professor 4 5%
Other 11 13%
Unknown 21 25%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 30 36%
Agricultural and Biological Sciences 18 21%
Medicine and Dentistry 6 7%
Business, Management and Accounting 1 1%
Computer Science 1 1%
Other 5 6%
Unknown 23 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 July 2022.
All research outputs
#2,239,778
of 25,257,066 outputs
Outputs from BMC Genomics
#580
of 11,206 outputs
Outputs of similar age
#41,279
of 314,089 outputs
Outputs of similar age from BMC Genomics
#22
of 200 outputs
Altmetric has tracked 25,257,066 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 11,206 research outputs from this source. They receive a mean Attention Score of 4.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,089 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 200 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.