Title |
HLA and non-HLA genes in Behçet’s disease: a multicentric study in the Spanish population
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Published in |
Arthritis Research & Therapy, October 2013
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DOI | 10.1186/ar4328 |
Pubmed ID | |
Authors |
Marco Antonio Montes-Cano, Marta Conde-Jaldón, José Raul García-Lozano, Lourdes Ortiz-Fernández, Norberto Ortego-Centeno, María Jesús Castillo-Palma, Gerard Espinosa, Genaro Graña-Gil, Miguel Angel González-Gay, Ana Celia Barnosi-Marín, Roser Solans, Patricia Fanlo, Teresa Camps, Santos Castañeda, Juan Sánchez-Bursón, Antonio Núñez-Roldán, Javier Martín, María Francisca González-Escribano |
Abstract |
According to genome wide association (GWA) studies as well as candidate gene approaches, Behçet's disease (BD) is associated with human leukocyte antigen (HLA)-A and HLA-B gene regions. The HLA-B51 has been consistently associated with the disease, but the role of other HLA class I molecules remains controversial. Recently, variants in non-HLA genes have also been associated with BD. The aims of this study were to further investigate the influence of the HLA region in BD and to explore the relationship with non-HLA genes recently described to be associated in other populations. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Spain | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hungary | 1 | 3% |
Unknown | 36 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 16% |
Student > Master | 5 | 14% |
Student > Ph. D. Student | 4 | 11% |
Student > Bachelor | 3 | 8% |
Student > Postgraduate | 3 | 8% |
Other | 12 | 32% |
Unknown | 4 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 16 | 43% |
Agricultural and Biological Sciences | 9 | 24% |
Biochemistry, Genetics and Molecular Biology | 4 | 11% |
Unspecified | 2 | 5% |
Immunology and Microbiology | 1 | 3% |
Other | 0 | 0% |
Unknown | 5 | 14% |