Title |
Distribution of erythrocyte binding antigen 175 (EBA-175) gene dimorphic alleles in Plasmodium falciparumfield isolates from Sudan
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Published in |
BMC Infectious Diseases, October 2013
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DOI | 10.1186/1471-2334-13-469 |
Pubmed ID | |
Authors |
Ahmed AM Adam, Ahmed AA Amine, Dina A Hassan, Waleed H Omer, Bakri Y Nour, Arulanantham Zechariah Jebakumar, Muntaser E Ibrahim, Nasreldin H Abdulhadi, Hiba S Mohamed |
Abstract |
The Erythrocyte Binding Antigen (EBA) 175 has been considered as one of the most important Plasmodium falciparum (P. falciparum) merozoite ligands that mediate invasion of the erythrocytes through their sialated receptor: Glycophorin A (GPA). The effect of the EBA 175 dimorphic alleles (F and C) on the severity of the disease is not yet fully understood. Therefore this study was designed to assess the distribution of the divergent dimorphic alleles of P. falciparum EBA-175 (F and C) in three different geographical areas in Sudan and the possible association of this dimorphism with the severity of the disease. |
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United Kingdom | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 4% |
Unknown | 22 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 4 | 17% |
Student > Bachelor | 4 | 17% |
Researcher | 3 | 13% |
Student > Postgraduate | 2 | 9% |
Student > Ph. D. Student | 2 | 9% |
Other | 5 | 22% |
Unknown | 3 | 13% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 5 | 22% |
Medicine and Dentistry | 5 | 22% |
Agricultural and Biological Sciences | 4 | 17% |
Unspecified | 1 | 4% |
Social Sciences | 1 | 4% |
Other | 1 | 4% |
Unknown | 6 | 26% |