Title |
Antiviral activity of carnosic acid against respiratory syncytial virus
|
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Published in |
Virology Journal, October 2013
|
DOI | 10.1186/1743-422x-10-303 |
Pubmed ID | |
Authors |
Han-Bo Shin, Myung-Soo Choi, Byeol Ryu, Na-Rae Lee, Hye-In Kim, Hye-Eun Choi, Jun Chang, Kyung-Tae Lee, Dae Sik Jang, Kyung-Soo Inn |
Abstract |
Human respiratory syncytial virus (hRSV) is a leading cause of severe lower respiratory infection and a major public health threat worldwide. To date, no vaccine or effective therapeutic agent has been developed. In a screen for potential therapeutic agents against hRSV, we discovered that an extract of Rosmarinus officinalis exerted a strong inhibitory effect against hRSV infection. Subsequent studies identified carnosic acid as a bioactive constituent responsible for anti-hRSV activity. Carnosic acid has been shown to exhibit potent antioxidant and anti-cancer activities. Anti-RSV activity of carnosic acid was further investigated in this study. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Lithuania | 1 | 1% |
Serbia | 1 | 1% |
Unknown | 94 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 17 | 18% |
Student > Master | 15 | 16% |
Researcher | 11 | 11% |
Student > Doctoral Student | 8 | 8% |
Student > Bachelor | 7 | 7% |
Other | 12 | 13% |
Unknown | 26 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 11 | 11% |
Biochemistry, Genetics and Molecular Biology | 10 | 10% |
Pharmacology, Toxicology and Pharmaceutical Science | 9 | 9% |
Medicine and Dentistry | 9 | 9% |
Immunology and Microbiology | 6 | 6% |
Other | 17 | 18% |
Unknown | 34 | 35% |