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Down-regulation of microglial activity attenuates axotomized nigral dopaminergic neuronal cell loss

Overview of attention for article published in BMC Neuroscience, October 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age and source (55th percentile)

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1 Google+ user

Citations

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8 Dimensions

Readers on

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20 Mendeley
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Title
Down-regulation of microglial activity attenuates axotomized nigral dopaminergic neuronal cell loss
Published in
BMC Neuroscience, October 2013
DOI 10.1186/1471-2202-14-112
Pubmed ID
Authors

Dae-Yong Song, Ha-Nul Yu, Chae-Ri Park, Jin-Sook Lee, Ji-Yong Lee, Byung-Gu Park, Ran-Sook Woo, Jung-Tae Han, Byung-Pil Cho, Tai-Kyoung Baik

Abstract

There is growing evidence that inflammatory processes of activated microglia could play an important role in the progression of nerve cell damage in neurodegenerative disorders such as Parkinson's disease and Alzheimer's disease which harbor features of chronic microglial activation, though the precise mechanism is unknown. In this study, we presented in vivo and ex vivo experimental evidences indicating that activated microglia could exacerbate the survival of axotomized dopaminergic neurons and that appropriate inactivation of microglia could be neuroprotective.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 25%
Student > Bachelor 4 20%
Other 2 10%
Researcher 2 10%
Professor 1 5%
Other 4 20%
Unknown 2 10%
Readers by discipline Count As %
Medicine and Dentistry 5 25%
Agricultural and Biological Sciences 4 20%
Biochemistry, Genetics and Molecular Biology 2 10%
Pharmacology, Toxicology and Pharmaceutical Science 2 10%
Engineering 2 10%
Other 4 20%
Unknown 1 5%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 October 2013.
All research outputs
#15,281,593
of 22,725,280 outputs
Outputs from BMC Neuroscience
#704
of 1,241 outputs
Outputs of similar age
#127,886
of 207,659 outputs
Outputs of similar age from BMC Neuroscience
#21
of 49 outputs
Altmetric has tracked 22,725,280 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,241 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 34th percentile – i.e., 34% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,659 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.