Title |
Non-coding-regulatory regions of human brain genes delineated by bacterial artificial chromosome knock-in mice
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Published in |
BMC Biology, October 2013
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DOI | 10.1186/1741-7007-11-106 |
Pubmed ID | |
Authors |
Jean-François Schmouth, Mauro Castellarin, Stéphanie Laprise, Kathleen G Banks, Russell J Bonaguro, Simone C McInerny, Lisa Borretta, Mahsa Amirabbasi, Andrea J Korecki, Elodie Portales-Casamar, Gary Wilson, Lisa Dreolini, Steven JM Jones, Wyeth W Wasserman, Daniel Goldowitz, Robert A Holt, Elizabeth M Simpson |
Abstract |
The next big challenge in human genetics is understanding the 98% of the genome that comprises non-coding DNA. Hidden in this DNA are sequences critical for gene regulation, and new experimental strategies are needed to understand the functional role of gene-regulation sequences in health and disease. In this study, we build upon our HuGX ('high-throughput human genes on the X chromosome') strategy to expand our understanding of human gene regulation in vivo. |
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France | 1 | 11% |
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Demographic breakdown
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Members of the public | 3 | 33% |
Science communicators (journalists, bloggers, editors) | 1 | 11% |
Mendeley readers
Geographical breakdown
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Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 4 | 19% |
Researcher | 3 | 14% |
Student > Ph. D. Student | 3 | 14% |
Student > Postgraduate | 2 | 10% |
Professor > Associate Professor | 2 | 10% |
Other | 3 | 14% |
Unknown | 4 | 19% |
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Psychology | 1 | 5% |
Immunology and Microbiology | 1 | 5% |
Other | 0 | 0% |
Unknown | 6 | 29% |