↓ Skip to main content

Parental exposures to occupational asthmagens and risk of autism spectrum disorder in a Danish population-based case-control study

Overview of attention for article published in Environmental Health, March 2017
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)

Mentioned by

blogs
1 blog
twitter
11 tweeters

Citations

dimensions_citation
5 Dimensions

Readers on

mendeley
72 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Parental exposures to occupational asthmagens and risk of autism spectrum disorder in a Danish population-based case-control study
Published in
Environmental Health, March 2017
DOI 10.1186/s12940-017-0230-8
Pubmed ID
Authors

Alison B. Singer, Igor Burstyn, Malene Thygesen, Preben Bo Mortensen, M. Daniele Fallin, Diana E. Schendel

Abstract

Environmental exposures and immune conditions during pregnancy could influence development of autism spectrum disorder (ASD) in offspring. However, few studies have examined immune-triggering exposures in relation to ASD. We evaluated the association between parental workplace exposures to risk factors for asthma ("asthmagens") and ASD. We conducted a population-based case-control study in the Danish population using register linkage. Our study population consisted of 11,869 ASD cases and 48,046 controls born from 1993 through 2007. Cases were identified by ICD-10 codes in the Danish Psychiatric Central Register. ASD cases and controls were linked to parental Danish International Standard Classification of Occupations (DISCO-88) job codes. Parental occupational asthmagen exposure was estimated by linking DISCO-88 codes to an asthma-specific job-exposure matrix. Our maternal analyses included 6706 case mothers and 29,359 control mothers employed during the pregnancy period. We found a weak inverse association between ASD and any maternal occupational asthmagen exposure, adjusting for sociodemographic covariates (adjusted OR: 0.92, 95% CI: 0.86-0.99). In adjusted analyses, including 7647 cases and 31,947 controls with employed fathers, paternal occupational asthmagen exposure was not associated with ASD (adjusted OR: 0.98, 95% CI: 0.92-1.05). We found a weak inverse association between maternal occupational asthmagen exposure and ASD, and a null association between paternal occupational exposure and ASD. We suggest that unmeasured confounding negatively biased the estimate, but that this unmeasured confounding is likely not strong enough to bring the effect above the null. Overall, our results were consistent with no positive association between parental asthmagen exposure and ASD in the children.

Twitter Demographics

The data shown below were collected from the profiles of 11 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 72 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 17%
Student > Master 12 17%
Student > Ph. D. Student 10 14%
Student > Bachelor 7 10%
Student > Doctoral Student 6 8%
Other 12 17%
Unknown 13 18%
Readers by discipline Count As %
Medicine and Dentistry 16 22%
Psychology 10 14%
Nursing and Health Professions 6 8%
Social Sciences 6 8%
Neuroscience 5 7%
Other 9 13%
Unknown 20 28%

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 September 2017.
All research outputs
#2,067,882
of 20,568,640 outputs
Outputs from Environmental Health
#412
of 1,415 outputs
Outputs of similar age
#42,602
of 281,434 outputs
Outputs of similar age from Environmental Health
#1
of 1 outputs
Altmetric has tracked 20,568,640 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,415 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 30.0. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 281,434 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them