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Endothelial cells do not arise from tumor-initiating cells in human hepatocellular carcinoma

Overview of attention for article published in BMC Cancer, October 2013
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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3 X users

Citations

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27 Mendeley
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Title
Endothelial cells do not arise from tumor-initiating cells in human hepatocellular carcinoma
Published in
BMC Cancer, October 2013
DOI 10.1186/1471-2407-13-485
Pubmed ID
Authors

Anand Ghanekar, Sharif Ahmed, Kui Chen, Oyedele Adeyi

Abstract

Conventional models of carcinogenesis suggest that tumors recruit blood vessel formation from normal host tissues. This concept has recently been challenged by prominent studies of glioblastoma, which suggest that intratumoral endothelial cells (ECs) may arise from cancer stem cells/tumor-initiating cells (TICs). Hepatocellular carcinoma (HCC) is a common, highly vascularized tumor with few effective therapies, against which anti-angiogenic strategies are being actively explored. TICs are felt to play a role in HCC pathobiology, but their contributions to tumor vasculature have not been studied.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 27 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 27 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 5 19%
Researcher 5 19%
Professor > Associate Professor 5 19%
Student > Master 5 19%
Student > Doctoral Student 3 11%
Other 3 11%
Unknown 1 4%
Readers by discipline Count As %
Medicine and Dentistry 13 48%
Agricultural and Biological Sciences 5 19%
Biochemistry, Genetics and Molecular Biology 3 11%
Nursing and Health Professions 2 7%
Psychology 1 4%
Other 1 4%
Unknown 2 7%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2013.
All research outputs
#14,180,180
of 22,727,570 outputs
Outputs from BMC Cancer
#3,356
of 8,270 outputs
Outputs of similar age
#118,890
of 211,693 outputs
Outputs of similar age from BMC Cancer
#41
of 103 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,270 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,693 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 103 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.