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Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders

Overview of attention for article published in Inflammation and Regeneration, April 2017
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Title
Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders
Published in
Inflammation and Regeneration, April 2017
DOI 10.1186/s41232-017-0038-5
Pubmed ID
Authors

Noriko Sugino, Tatsuo Ichinohe, Akifumi Takaori-Kondo, Taira Maekawa, Yasuo Miura

Abstract

The therapeutic effects of mesenchymal stromal/stem cells (MSCs) are mainly based on three characteristics: immunomodulation, tissue regeneration, and hematopoietic support. Cell therapy using culture-expanded MSCs is effective in some intractable bone and hemato-immune disorders; however, its efficacy is limited. In this article, we review the previous efforts to improve the clinical outcomes of cell therapy using MSCs for such disorders. We describe pharmacological targeting of endogenous bone marrow-derived MSCs as a crucial quality-based intervention to establish more effective MSC-based therapies.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 13 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 13 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 23%
Lecturer 2 15%
Student > Bachelor 1 8%
Other 1 8%
Student > Ph. D. Student 1 8%
Other 1 8%
Unknown 4 31%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 3 23%
Medicine and Dentistry 2 15%
Immunology and Microbiology 1 8%
Nursing and Health Professions 1 8%
Physics and Astronomy 1 8%
Other 1 8%
Unknown 4 31%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 May 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Inflammation and Regeneration
#206
of 258 outputs
Outputs of similar age
#249,085
of 323,671 outputs
Outputs of similar age from Inflammation and Regeneration
#6
of 6 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 258 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 6th percentile – i.e., 6% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 323,671 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one.