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Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell

Overview of attention for article published in Journal of Translational Medicine, October 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

blogs
1 blog
twitter
3 X users
patent
2 patents

Citations

dimensions_citation
78 Dimensions

Readers on

mendeley
57 Mendeley
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Title
Polydatin, a natural precursor of resveratrol, induces cell cycle arrest and differentiation of human colorectal Caco-2 cell
Published in
Journal of Translational Medicine, October 2013
DOI 10.1186/1479-5876-11-264
Pubmed ID
Authors

Salvatore De Maria, Ilaria Scognamiglio, Angela Lombardi, Nicola Amodio, Michele Caraglia, Maria Cartenì, Gianpietro Ravagnan, Paola Stiuso

Abstract

Human colon adenocarcinoma cells are resistant to chemotherapeutic agents, such as anthracyclines, that induce death by increasing the reactive oxygen species. A number of studies have been focused on chemo-preventive use of resveratrol as antioxidant against cardiovascular diseases, aging and cancer. While resveratrol cytotoxic action was due to its pro-oxidant properties. In this study, we investigate whether the Resveratrol (trans-3,5,49-trihydroxystilbene) and its natural precursor Polydatin (resveratrol-3-O-b-mono-D-glucoside, the glycoside form of resveratrol) combination, might have a cooperative antitumor effect on either growing or differentiated human adenocarcinoma colon cancer cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Kenya 1 2%
Unknown 56 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 8 14%
Student > Ph. D. Student 8 14%
Student > Bachelor 6 11%
Student > Doctoral Student 5 9%
Other 4 7%
Other 9 16%
Unknown 17 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 21%
Biochemistry, Genetics and Molecular Biology 7 12%
Medicine and Dentistry 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 4 7%
Chemistry 2 4%
Other 8 14%
Unknown 19 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 February 2020.
All research outputs
#2,406,523
of 22,727,570 outputs
Outputs from Journal of Translational Medicine
#388
of 3,974 outputs
Outputs of similar age
#23,641
of 211,693 outputs
Outputs of similar age from Journal of Translational Medicine
#3
of 69 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,974 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,693 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.