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Parametric sensitivity analysis for biochemical reaction networks based on pathwise information theory

Overview of attention for article published in BMC Bioinformatics, October 2013
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1 X user

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Title
Parametric sensitivity analysis for biochemical reaction networks based on pathwise information theory
Published in
BMC Bioinformatics, October 2013
DOI 10.1186/1471-2105-14-311
Pubmed ID
Authors

Yannis Pantazis, Markos A Katsoulakis, Dionisios G Vlachos

Abstract

Stochastic modeling and simulation provide powerful predictive methods for the intrinsic understanding of fundamental mechanisms in complex biochemical networks. Typically, such mathematical models involve networks of coupled jump stochastic processes with a large number of parameters that need to be suitably calibrated against experimental data. In this direction, the parameter sensitivity analysis of reaction networks is an essential mathematical and computational tool, yielding information regarding the robustness and the identifiability of model parameters. However, existing sensitivity analysis approaches such as variants of the finite difference method can have an overwhelming computational cost in models with a high-dimensional parameter space.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 67 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 7%
Germany 1 1%
Chile 1 1%
Hungary 1 1%
Singapore 1 1%
France 1 1%
Venezuela, Bolivarian Republic of 1 1%
Belgium 1 1%
Unknown 55 82%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 31%
Student > Ph. D. Student 12 18%
Student > Master 7 10%
Other 5 7%
Student > Bachelor 4 6%
Other 12 18%
Unknown 6 9%
Readers by discipline Count As %
Agricultural and Biological Sciences 17 25%
Engineering 9 13%
Mathematics 8 12%
Physics and Astronomy 5 7%
Computer Science 4 6%
Other 14 21%
Unknown 10 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2013.
All research outputs
#18,351,676
of 22,727,570 outputs
Outputs from BMC Bioinformatics
#6,300
of 7,266 outputs
Outputs of similar age
#157,975
of 212,053 outputs
Outputs of similar age from BMC Bioinformatics
#94
of 116 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,266 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
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We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.