Title |
HIV-1 tropism: a comparison between RNA and proviral DNA in routine clinical samples from Chilean patients
|
---|---|
Published in |
Virology Journal, October 2013
|
DOI | 10.1186/1743-422x-10-318 |
Pubmed ID | |
Authors |
Pablo Ferrer, Luisa Montecinos, Mario Tello, Rocio Tordecilla, Consuelo Rodríguez, Marcela Ferrés, Carlos M Pérez, Carlos Beltrán, Maria A Guzmán, Alejandro Afani |
Abstract |
HIV in Chile has a notification rate of 0.01%. Coreceptor antagonists are a family of antiretroviral drugs that are used with the prior knowledge of patients HIV-1 tropism. Viral RNA-based tropism detection requires a plasma viral load ≥1000 copies/mL, while proviral DNA-based detection can be performed regardless of plasma viral load. This test is useful in patients with low or undetectable viral loads and would benefit with a proper therapy. The aim of this study was to determine the correlation between HIV RNA and proviral genotypic DNA tropism tests. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
El Salvador | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 36% |
Student > Master | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Librarian | 2 | 8% |
Student > Ph. D. Student | 2 | 8% |
Other | 5 | 20% |
Unknown | 2 | 8% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 7 | 28% |
Biochemistry, Genetics and Molecular Biology | 5 | 20% |
Immunology and Microbiology | 3 | 12% |
Medicine and Dentistry | 3 | 12% |
Social Sciences | 1 | 4% |
Other | 2 | 8% |
Unknown | 4 | 16% |