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Osteogenesis evaluation of duck’s feet-derived collagen/hydroxyapatite sponges immersed in dexamethasone

Overview of attention for article published in Biomaterials Research, February 2017
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Title
Osteogenesis evaluation of duck’s feet-derived collagen/hydroxyapatite sponges immersed in dexamethasone
Published in
Biomaterials Research, February 2017
DOI 10.1186/s40824-017-0088-4
Pubmed ID
Authors

Yeon Ji Kook, Dae Hoon Lee, Jeong Eun Song, Nirmalya Tripathy, Yoo Shin Jeon, Ha Yan Jeon, Joaquim M. Oliveira, Rui L. Reis, Gilson Khang

Abstract

The aim of this study was to investigate the osteogenesis effects of DC and DC/HAp sponge immersed in without and with dexamethasone. The experimental groups in this study were DC and DC/HAp sponge immersed in without dexamethasone (Dex(-)DC and Dex(-)-DC/HAp group) and with dexamethasone (Dex(+)-DC and Dex(+)-DC/HAp group). We characterized DC and DC/HAp sponge using compressive strength, scanning electron microscopy (SEM). Also, osteogenic differentiation of BMSCs on sponge (Dex(-)DC, Dex(-)-DC/HAp, Dex(+)-DC and Dex(+)-DC/HAp group) was assessed by SEM, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide (MTT) assay, alkaline phosphatase (ALP) activity assay and reverse transcription-PCR (RT-PCR). In this study, we assessed osteogenic differentiation of BMSCs on Duck's feet-derived collagen (DC)/HAp sponge immersed with dexamethasone Dex(+)-DC/HAp. These results showed that Dex(+)-DC/HAp group increased cell proliferation and osteogenic differentiation of BMSCs during 28 days. From these results, Dex(+)-DC/HAp can be envisioned as a potential biomaterial for bone regeneration applications.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 21 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 33%
Researcher 4 19%
Student > Bachelor 3 14%
Professor 1 5%
Lecturer > Senior Lecturer 1 5%
Other 0 0%
Unknown 5 24%
Readers by discipline Count As %
Engineering 4 19%
Agricultural and Biological Sciences 3 14%
Materials Science 3 14%
Biochemistry, Genetics and Molecular Biology 2 10%
Chemistry 2 10%
Other 2 10%
Unknown 5 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2017.
All research outputs
#20,660,571
of 25,382,440 outputs
Outputs from Biomaterials Research
#142
of 197 outputs
Outputs of similar age
#251,914
of 324,444 outputs
Outputs of similar age from Biomaterials Research
#1
of 1 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 197 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
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