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Osteogenesis evaluation of duck’s feet-derived collagen/hydroxyapatite sponges immersed in dexamethasone

Overview of attention for article published in Biomaterials Research, February 2017
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Title
Osteogenesis evaluation of duck’s feet-derived collagen/hydroxyapatite sponges immersed in dexamethasone
Published in
Biomaterials Research, February 2017
DOI 10.1186/s40824-017-0088-4
Pubmed ID
Authors

Yeon Ji Kook, Dae Hoon Lee, Jeong Eun Song, Nirmalya Tripathy, Yoo Shin Jeon, Ha Yan Jeon, Joaquim M. Oliveira, Rui L. Reis, Gilson Khang

Abstract

The aim of this study was to investigate the osteogenesis effects of DC and DC/HAp sponge immersed in without and with dexamethasone. The experimental groups in this study were DC and DC/HAp sponge immersed in without dexamethasone (Dex(-)DC and Dex(-)-DC/HAp group) and with dexamethasone (Dex(+)-DC and Dex(+)-DC/HAp group). We characterized DC and DC/HAp sponge using compressive strength, scanning electron microscopy (SEM). Also, osteogenic differentiation of BMSCs on sponge (Dex(-)DC, Dex(-)-DC/HAp, Dex(+)-DC and Dex(+)-DC/HAp group) was assessed by SEM, 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyltetrazoliumbromide (MTT) assay, alkaline phosphatase (ALP) activity assay and reverse transcription-PCR (RT-PCR). In this study, we assessed osteogenic differentiation of BMSCs on Duck's feet-derived collagen (DC)/HAp sponge immersed with dexamethasone Dex(+)-DC/HAp. These results showed that Dex(+)-DC/HAp group increased cell proliferation and osteogenic differentiation of BMSCs during 28 days. From these results, Dex(+)-DC/HAp can be envisioned as a potential biomaterial for bone regeneration applications.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 17 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 35%
Researcher 4 24%
Student > Bachelor 3 18%
Professor 1 6%
Unknown 3 18%
Readers by discipline Count As %
Engineering 3 18%
Agricultural and Biological Sciences 3 18%
Materials Science 3 18%
Biochemistry, Genetics and Molecular Biology 2 12%
Chemistry 2 12%
Other 1 6%
Unknown 3 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 April 2017.
All research outputs
#10,437,118
of 13,090,166 outputs
Outputs from Biomaterials Research
#27
of 44 outputs
Outputs of similar age
#190,962
of 262,769 outputs
Outputs of similar age from Biomaterials Research
#2
of 2 outputs
Altmetric has tracked 13,090,166 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 44 research outputs from this source. They receive a mean Attention Score of 2.4. This one scored the same or higher as 17 of them.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 262,769 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 2 others from the same source and published within six weeks on either side of this one.