Title |
Clinical and laboratory predictive markers for acute dengue infection
|
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Published in |
Journal of Biomedical Science, October 2013
|
DOI | 10.1186/1423-0127-20-75 |
Pubmed ID | |
Authors |
Tzong-Shiann Ho, Shih-Min Wang, Yee-Shin Lin, Ching-Chuan Liu |
Abstract |
Early diagnosis of dengue virus infection during the febrile stage is essential for adjusting appropriate management. This study is to identify the predictive markers of clinical and laboratory findings in the acute stage of dengue infection during a major outbreak of dengue virus type 1 that occurred in southern Taiwan during 2007. A retrospective, hospital-based study was conducted at a university hospital in southern Taiwan from January to December, 2007. Patient who was reported for clinically suspected dengue infection was enrolled. Laboratory-positive dengue cases are confirmed by enzyme-linked immunosorbent assay of specific dengue IgM, fourfold increase of dengue-specific IgG titers in convalescent serum, or by reverse transcription-polymerase chain reaction (RT-PCR) of dengue virus. |
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