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Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer

Overview of attention for article published in BMC Cancer, November 2013
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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2 X users

Citations

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37 Dimensions

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48 Mendeley
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Title
Identification of the angiogenic gene signature induced by EGF and hypoxia in colorectal cancer
Published in
BMC Cancer, November 2013
DOI 10.1186/1471-2407-13-518
Pubmed ID
Authors

Tak L Khong, Ngayu Thairu, Helene Larsen, Peter M Dawson, Serafim Kiriakidis, Ewa M Paleolog

Abstract

Colorectal cancer (CRC) is characterised by hypoxia, which activates gene transcription through hypoxia-inducible factors (HIF), as well as by expression of epidermal growth factor (EGF) and EGF receptors, targeting of which has been demonstrated to provide therapeutic benefit in CRC. Although EGF has been demonstrated to induce expression of angiogenic mediators, potential interactions in CRC between EGF-mediated signalling and the hypoxia/HIF pathway remain uncharacterised.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 2%
Brazil 1 2%
Unknown 46 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 25%
Student > Bachelor 7 15%
Researcher 6 13%
Student > Master 6 13%
Other 2 4%
Other 9 19%
Unknown 6 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 27%
Medicine and Dentistry 12 25%
Biochemistry, Genetics and Molecular Biology 11 23%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Unspecified 1 2%
Other 4 8%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 November 2013.
All research outputs
#14,181,583
of 22,729,647 outputs
Outputs from BMC Cancer
#3,356
of 8,270 outputs
Outputs of similar age
#119,665
of 213,827 outputs
Outputs of similar age from BMC Cancer
#43
of 110 outputs
Altmetric has tracked 22,729,647 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,270 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 56% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 213,827 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.