Title |
Periodontal disease, Porphyromonas gingivalis, and rheumatoid arthritis: what triggers autoimmunity and clinical disease?
|
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Published in |
Arthritis Research & Therapy, October 2013
|
DOI | 10.1186/ar4360 |
Pubmed ID | |
Authors |
Jose U Scher, Steven B Abramson |
Abstract |
Rheumatoid arthritis, currently regarded as a complex multifactorial disease, was initially characterized as such at the turn of the 19th century. Ever since, multiple lines of investigation have attempted to elucidate the etiological factor(s) involved in disease incidence. Genes--including those risk alleles within HLA-DR4--have been implicated but are insufficient to explain the vast majority of cases. Several environmental factors, therefore, are being studied. Among them, the role of periodontal disease and Porphyromonas gingivalis in the pathogenesis of rheumatoid arthritis has attracted both clinical and bench interest given supportive epidemiologic and mechanistic data. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hungary | 1 | 2% |
Russia | 1 | 2% |
Unknown | 56 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 11 | 19% |
Student > Ph. D. Student | 10 | 17% |
Researcher | 9 | 16% |
Student > Bachelor | 8 | 14% |
Student > Doctoral Student | 2 | 3% |
Other | 7 | 12% |
Unknown | 11 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 18 | 31% |
Biochemistry, Genetics and Molecular Biology | 9 | 16% |
Agricultural and Biological Sciences | 9 | 16% |
Immunology and Microbiology | 2 | 3% |
Nursing and Health Professions | 1 | 2% |
Other | 4 | 7% |
Unknown | 15 | 26% |