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Alcohol use disorders among people living with HIV/AIDS in Southern Brazil: prevalence, risk factors and biological markers outcomes

Overview of attention for article published in BMC Infectious Diseases, April 2017
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Title
Alcohol use disorders among people living with HIV/AIDS in Southern Brazil: prevalence, risk factors and biological markers outcomes
Published in
BMC Infectious Diseases, April 2017
DOI 10.1186/s12879-017-2374-0
Pubmed ID
Authors

Cláudio Moss da Silva, Raúl Andrés Mendoza-Sassi, Luisa Dias da Mota, Maíba Mikhael Nader, Ana Maria Barral de Martinez

Abstract

Alcohol abuse is an important public health problem, frequently unrecognized among people living with HIV/AIDS (PLWHA), and requires investigation and intervention. It is usually associated with lower adherence to highly active antiretroviral therapy (HAART). It can also produce adverse clinical outcomes, such as changes in certain HIV markers, particularly CD4 cell counts and HIV viral loads (VLs). Thus, this study aimed to evaluate the prevalence of alcohol abuse among PLWHA, its associated risk factors and effects on CD4 cell counts and HIV VLs in southern Brazil. Between December 2012 and July 2013, 343 patients were interviewed at a reference hospital in southern Brazil. The instrument used was the Alcohol Use Disorder Identification Test (AUDIT), and a cutoff of eight points or more was applied. Socioeconomic, demographic, clinical and laboratory data were also collected. The statistical analysis included a Poisson regression to evaluate the factors associated with alcohol use disorder, and a linear regression was performed to assess the relationship between AUDIT scores and CD4 cell counts and HIV VLs. Alcohol abuse was present in 28.6% of the respondents, and possible dependence was present in 5%. The risk factors identified included being male, mixed or black skin color, low education and the use of intravenous or inhaled drugs. A higher AUDIT score was associated with a lower CD4 cell count but was not associated with higher HIV VL values. Our results show the importance of screening for alcohol abuse in this group. The prevalence of alcohol abuse was high, and it was associated with socioeconomic factors and the use of illicit drugs. Moreover, AUDIT score negatively affected CD4 cell counts as well.

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Mendeley readers

Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 100 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 15 15%
Student > Bachelor 12 12%
Researcher 11 11%
Student > Postgraduate 9 9%
Student > Ph. D. Student 6 6%
Other 18 18%
Unknown 29 29%
Readers by discipline Count As %
Medicine and Dentistry 26 26%
Nursing and Health Professions 13 13%
Psychology 8 8%
Pharmacology, Toxicology and Pharmaceutical Science 6 6%
Agricultural and Biological Sciences 2 2%
Other 9 9%
Unknown 36 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2017.
All research outputs
#20,413,129
of 22,963,381 outputs
Outputs from BMC Infectious Diseases
#6,506
of 7,706 outputs
Outputs of similar age
#270,218
of 310,118 outputs
Outputs of similar age from BMC Infectious Diseases
#139
of 171 outputs
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We're also able to compare this research output to 171 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.