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Activation of pro-oncogenic pathways in colorectal hyperplastic polyps

Overview of attention for article published in BMC Cancer, November 2013
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

Mentioned by

wikipedia
1 Wikipedia page

Citations

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4 Dimensions

Readers on

mendeley
15 Mendeley
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Title
Activation of pro-oncogenic pathways in colorectal hyperplastic polyps
Published in
BMC Cancer, November 2013
DOI 10.1186/1471-2407-13-531
Pubmed ID
Authors

Catherine Do, Claudine Bertrand, Julien Palasse, Marie-Bernadette Delisle, Elizabeth Cohen-Jonathan-Moyal, Catherine Seva

Abstract

In contrast to sessile serrated adenomas and traditional serrated adenomas which are associated with a significant cancer risk, the role of hyperplastic polyps (HP) in colorectal carcinogenesis as well as the molecular mechanisms underlying their development remain controversial and still need to be clarified. Several reports suggest that a subset of HP may represent precursor lesions of some colorectal cancers. However, biomarkers are needed to identify the subset of HP that may have a malignant potential. The hormone precursor, progastrin (PG) has been involved in colon carcinogenesis and is known to activate pro-oncogenic pathways such as the ERK or the STAT3 pathway. We therefore analyzed PG expression and the activation of these signaling factors in HP.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 15 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 7%
Unknown 14 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 5 33%
Student > Ph. D. Student 4 27%
Professor 1 7%
Student > Master 1 7%
Other 1 7%
Other 0 0%
Unknown 3 20%
Readers by discipline Count As %
Medicine and Dentistry 7 47%
Agricultural and Biological Sciences 3 20%
Veterinary Science and Veterinary Medicine 1 7%
Unknown 4 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 06 July 2020.
All research outputs
#7,435,148
of 22,729,647 outputs
Outputs from BMC Cancer
#2,055
of 8,270 outputs
Outputs of similar age
#71,684
of 215,945 outputs
Outputs of similar age from BMC Cancer
#26
of 106 outputs
Altmetric has tracked 22,729,647 research outputs across all sources so far. This one is in the 44th percentile – i.e., 44% of other outputs scored the same or lower than it.
So far Altmetric has tracked 8,270 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 215,945 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 106 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.