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The Drosophila early ovarian transcriptome provides insight to the molecular causes of recombination rate variation across genomes

Overview of attention for article published in BMC Genomics, November 2013
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Title
The Drosophila early ovarian transcriptome provides insight to the molecular causes of recombination rate variation across genomes
Published in
BMC Genomics, November 2013
DOI 10.1186/1471-2164-14-794
Pubmed ID
Authors

Andrew B Adrian, Josep M Comeron

Abstract

Evidence in yeast indicates that gene expression is correlated with recombination activity and double-strand break (DSB) formation in some hotspots. Studies of nucleosome occupancy in yeast and mice also suggest that open chromatin influences the formation of DSBs. In Drosophila melanogaster, high-resolution recombination maps show an excess of DSBs within annotated transcripts relative to intergenic sequences. The impact of active transcription on recombination landscapes, however, remains unexplored in a multicellular organism. We then investigated the transcription profile during early meiosis in D. melanogaster females to obtain a glimpse at the relevant transcriptional dynamics during DSB formation, and test the specific hypothesis that DSBs preferentially target transcriptionally active genomic regions.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 7%
Netherlands 1 2%
Germany 1 2%
Unknown 37 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 26%
Researcher 10 24%
Student > Master 4 10%
Student > Postgraduate 3 7%
Professor > Associate Professor 3 7%
Other 6 14%
Unknown 5 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 27 64%
Biochemistry, Genetics and Molecular Biology 8 19%
Computer Science 2 5%
Social Sciences 1 2%
Unknown 4 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 November 2013.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from BMC Genomics
#9,840
of 11,244 outputs
Outputs of similar age
#197,535
of 223,561 outputs
Outputs of similar age from BMC Genomics
#180
of 226 outputs
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So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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We're also able to compare this research output to 226 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.