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A novel phenotypic dissimilarity method for image-based high-throughput screens

Overview of attention for article published in BMC Bioinformatics, November 2013
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Mentioned by

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3 X users

Citations

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63 Mendeley
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Title
A novel phenotypic dissimilarity method for image-based high-throughput screens
Published in
BMC Bioinformatics, November 2013
DOI 10.1186/1471-2105-14-336
Pubmed ID
Authors

Xian Zhang, Michael Boutros

Abstract

Discovering functional relationships of genes through cell-based phenotyping has become an important approach in functional genomics. High-throughput imaging offers the ability to quantitatively assess complex phenotypes after perturbation by RNA interference (RNAi). Such image-based high-throughput RNAi screening studies have facilitated the discovery of novel components of gene networks and their interactions. Images generated by automated microscopy are typically analyzed by extracting quantitative features of individual cells, resulting in large multidimensional data sets. Robust and sensitive methods to interpret these data sets and to derive biologically relevant information in a high-throughput and unbiased manner remain to be developed.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 63 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 2 3%
Brazil 1 2%
United Kingdom 1 2%
Canada 1 2%
Spain 1 2%
United States 1 2%
Unknown 56 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 21 33%
Student > Ph. D. Student 13 21%
Student > Bachelor 7 11%
Student > Master 5 8%
Professor 2 3%
Other 5 8%
Unknown 10 16%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 41%
Biochemistry, Genetics and Molecular Biology 11 17%
Computer Science 7 11%
Engineering 4 6%
Medicine and Dentistry 2 3%
Other 2 3%
Unknown 11 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 March 2014.
All research outputs
#15,866,607
of 23,577,654 outputs
Outputs from BMC Bioinformatics
#5,477
of 7,400 outputs
Outputs of similar age
#193,004
of 305,835 outputs
Outputs of similar age from BMC Bioinformatics
#66
of 104 outputs
Altmetric has tracked 23,577,654 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,400 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.4. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 305,835 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 104 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.