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miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells

Overview of attention for article published in BMC Medicine, June 2008
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (94th percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users
patent
5 patents
wikipedia
1 Wikipedia page

Citations

dimensions_citation
799 Dimensions

Readers on

mendeley
433 Mendeley
citeulike
6 CiteULike
connotea
1 Connotea
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Title
miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells
Published in
BMC Medicine, June 2008
DOI 10.1186/1741-7015-6-14
Pubmed ID
Authors

Joachim Silber, Daniel A Lim, Claudia Petritsch, Anders I Persson, Alika K Maunakea, Mamie Yu, Scott R Vandenberg, David G Ginzinger, C David James, Joseph F Costello, Gabriele Bergers, William A Weiss, Arturo Alvarez-Buylla, J Graeme Hodgson

Abstract

Glioblastoma multiforme (GBM) is an invariably fatal central nervous system tumor despite treatment with surgery, radiation, and chemotherapy. Further insights into the molecular and cellular mechanisms that drive GBM formation are required to improve patient outcome. MicroRNAs are emerging as important regulators of cellular differentiation and proliferation, and have been implicated in the etiology of a variety of cancers, yet the role of microRNAs in GBM remains poorly understood. In this study, we investigated the role of microRNAs in regulating the differentiation and proliferation of neural stem cells and glioblastoma-multiforme tumor cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 433 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 10 2%
Brazil 3 <1%
Germany 2 <1%
Denmark 2 <1%
Belgium 2 <1%
Australia 1 <1%
Hong Kong 1 <1%
Italy 1 <1%
France 1 <1%
Other 7 2%
Unknown 403 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 93 21%
Researcher 90 21%
Student > Master 53 12%
Student > Bachelor 51 12%
Student > Doctoral Student 23 5%
Other 79 18%
Unknown 44 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 145 33%
Medicine and Dentistry 90 21%
Biochemistry, Genetics and Molecular Biology 71 16%
Neuroscience 40 9%
Engineering 6 1%
Other 31 7%
Unknown 50 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 17. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 February 2021.
All research outputs
#1,923,348
of 23,881,329 outputs
Outputs from BMC Medicine
#1,301
of 3,613 outputs
Outputs of similar age
#4,895
of 83,749 outputs
Outputs of similar age from BMC Medicine
#1
of 7 outputs
Altmetric has tracked 23,881,329 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,613 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 44.6. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 83,749 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them