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Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity

Overview of attention for article published in Journal of Translational Medicine, November 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

Mentioned by

twitter
1 tweeter
wikipedia
1 Wikipedia page

Citations

dimensions_citation
47 Dimensions

Readers on

mendeley
54 Mendeley
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Title
Targeting Cdc42 with the small molecule drug AZA197 suppresses primary colon cancer growth and prolongs survival in a preclinical mouse xenograft model by downregulation of PAK1 activity
Published in
Journal of Translational Medicine, November 2013
DOI 10.1186/1479-5876-11-295
Pubmed ID
Authors

Karin Zins, Sandun Gunawardhana, Trevor Lucas, Dietmar Abraham, Seyedhossein Aharinejad

Abstract

Rho GTPases play important roles in cytoskeleton organization, cell cycle progression and are key regulators of tumor progression. Strategies to modulate increased Rho GTPase activities during cancer progression could have therapeutic potential.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 2%
Germany 1 2%
Unknown 52 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 22%
Researcher 10 19%
Student > Master 8 15%
Student > Doctoral Student 4 7%
Student > Bachelor 4 7%
Other 8 15%
Unknown 8 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 33%
Biochemistry, Genetics and Molecular Biology 11 20%
Medicine and Dentistry 8 15%
Chemistry 3 6%
Veterinary Science and Veterinary Medicine 1 2%
Other 4 7%
Unknown 9 17%

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2016.
All research outputs
#6,701,236
of 21,356,145 outputs
Outputs from Journal of Translational Medicine
#1,050
of 3,682 outputs
Outputs of similar age
#88,557
of 303,868 outputs
Outputs of similar age from Journal of Translational Medicine
#89
of 264 outputs
Altmetric has tracked 21,356,145 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 3,682 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.1. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 303,868 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 264 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.