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Inferring viral quasispecies spectra from 454 pyrosequencing reads

Overview of attention for article published in BMC Bioinformatics, July 2011
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Title
Inferring viral quasispecies spectra from 454 pyrosequencing reads
Published in
BMC Bioinformatics, July 2011
DOI 10.1186/1471-2105-12-s6-s1
Pubmed ID
Authors

Irina Astrovskaya, Bassam Tork, Serghei Mangul, Kelly Westbrooks, Ion Măndoiu, Peter Balfe, Alex Zelikovsky

Abstract

RNA viruses infecting a host usually exist as a set of closely related sequences, referred to as quasispecies. The genomic diversity of viral quasispecies is a subject of great interest, particularly for chronic infections, since it can lead to resistance to existing therapies. High-throughput sequencing is a promising approach to characterizing viral diversity, but unfortunately standard assembly software was originally designed for single genome assembly and cannot be used to simultaneously assemble and estimate the abundance of multiple closely related quasispecies sequences.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 162 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Brazil 7 4%
United States 4 2%
France 2 1%
Switzerland 2 1%
Sweden 2 1%
Canada 2 1%
Norway 1 <1%
United Kingdom 1 <1%
Belgium 1 <1%
Other 3 2%
Unknown 137 85%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 49 30%
Researcher 35 22%
Student > Master 26 16%
Student > Bachelor 11 7%
Professor > Associate Professor 8 5%
Other 24 15%
Unknown 9 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 90 56%
Biochemistry, Genetics and Molecular Biology 22 14%
Computer Science 20 12%
Medicine and Dentistry 7 4%
Engineering 4 2%
Other 10 6%
Unknown 9 6%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2023.
All research outputs
#17,193,840
of 25,257,066 outputs
Outputs from BMC Bioinformatics
#5,634
of 7,664 outputs
Outputs of similar age
#90,351
of 124,800 outputs
Outputs of similar age from BMC Bioinformatics
#63
of 85 outputs
Altmetric has tracked 25,257,066 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 7,664 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 18th percentile – i.e., 18% of its peers scored the same or lower than it.
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We're also able to compare this research output to 85 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.