Title |
Oral probiotic and prevention of Pseudomonas aeruginosa infections: a randomized, double-blind, placebo-controlled pilot study in intensive care unit patients
|
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Published in |
Critical Care, May 2008
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DOI | 10.1186/cc6907 |
Pubmed ID | |
Authors |
Christiane Forestier, Dominique Guelon, Valérie Cluytens, Thierry Gillart, Jacques Sirot, Christophe De Champs |
Abstract |
Preventing carriage of potentially pathogenic micro-organisms from the aerodigestive tract is an infection control strategy used to reduce the occurrence of ventilator-associated pneumonia in intensive care units. However, antibiotic use in selective decontamination protocols is controversial. The purpose of this study was to investigate the effect of oral administration of a probiotic, namely Lactobacillus, on gastric and respiratory tract colonization/infection with Pseudomonas aeruginosa strains. Our hypothesis was that an indigenous flora should exhibit a protective effect against secondary colonization. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Indonesia | 1 | <1% |
Uruguay | 1 | <1% |
United Kingdom | 1 | <1% |
Puerto Rico | 1 | <1% |
Spain | 1 | <1% |
Japan | 1 | <1% |
Unknown | 144 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 23 | 15% |
Student > Master | 22 | 15% |
Other | 17 | 11% |
Student > Bachelor | 11 | 7% |
Professor | 9 | 6% |
Other | 36 | 24% |
Unknown | 32 | 21% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 60 | 40% |
Agricultural and Biological Sciences | 16 | 11% |
Nursing and Health Professions | 12 | 8% |
Immunology and Microbiology | 9 | 6% |
Pharmacology, Toxicology and Pharmaceutical Science | 6 | 4% |
Other | 12 | 8% |
Unknown | 35 | 23% |