Title |
The 6R’s of drug induced nephrotoxicity
|
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Published in |
BMC Nephrology, April 2017
|
DOI | 10.1186/s12882-017-0536-3 |
Pubmed ID | |
Authors |
Linda Awdishu, Ravindra L. Mehta |
Abstract |
Drug induced kidney injury is a frequent adverse event which contributes to morbidity and increased healthcare utilization. Our current knowledge of drug induced kidney disease is limited due to varying definitions of kidney injury, incomplete assessment of concurrent risk factors and lack of long term outcome reporting. Electronic surveillance presents a powerful tool to identify susceptible populations, improve recognition of events and provide decision support on preventative strategies or early intervention in the case of injury. Research in the area of biomarkers for detecting kidney injury and genetic predisposition for this adverse event will enhance detection of injury, identify those susceptible to injury and likely mitigate risk. In this review we will present a 6R framework to identify and mange drug induced kidney injury - risk, recognition, response, renal support, rehabilitation and research. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 5 | 20% |
Ecuador | 2 | 8% |
Egypt | 1 | 4% |
Bolivia, Plurinational State of | 1 | 4% |
Japan | 1 | 4% |
Brazil | 1 | 4% |
India | 1 | 4% |
Australia | 1 | 4% |
Sao Tome and Principe | 1 | 4% |
Other | 3 | 12% |
Unknown | 8 | 32% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 17 | 68% |
Practitioners (doctors, other healthcare professionals) | 7 | 28% |
Scientists | 1 | 4% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 293 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 38 | 13% |
Student > Bachelor | 33 | 11% |
Student > Ph. D. Student | 25 | 9% |
Researcher | 24 | 8% |
Student > Postgraduate | 18 | 6% |
Other | 47 | 16% |
Unknown | 108 | 37% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 65 | 22% |
Pharmacology, Toxicology and Pharmaceutical Science | 52 | 18% |
Biochemistry, Genetics and Molecular Biology | 16 | 5% |
Agricultural and Biological Sciences | 9 | 3% |
Nursing and Health Professions | 9 | 3% |
Other | 26 | 9% |
Unknown | 116 | 40% |