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Expression of inflammation-related genes is associated with adipose tissue location in horses

Overview of attention for article published in BMC Veterinary Research, December 2013
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2 X users

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44 Mendeley
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Title
Expression of inflammation-related genes is associated with adipose tissue location in horses
Published in
BMC Veterinary Research, December 2013
DOI 10.1186/1746-6148-9-240
Pubmed ID
Authors

Lien Bruynsteen, Tim Erkens, Luc J Peelman, Richard Ducatelle, Geert PJ Janssens, Patricia A Harris, Myriam Hesta

Abstract

In humans, adipose tissue (AT) originating from different depots shows varying gene expression profiles. In horses, the risk of certain metabolic disorders may also be influenced by the impact of specific AT depots. Macrophage infiltration in human and rat AT is considered to be a source of inflammatory changes. In horses, this relationship has not been extensively studied yet. Reverse transcription quantitative real-time polymerase chain reaction (RT-qPCR), a useful method to evaluate differences in mRNA expression across different tissues, can be used to evaluate differences between equine AT depots. For a correct interpretation of the RT-qPCR results, expression data have to be normalized by the use of validated reference genes. The main objectives of this study were to compare mRNA expression of inflammation-related genes, as well as adipocyte morphology and number between different equine AT depots; and in addition, to investigate the presence of antigen presenting cells in equine AT and any potential relationship with adipokine mRNA expression.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 44 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
South Africa 1 2%
Unknown 42 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 6 14%
Other 5 11%
Student > Bachelor 5 11%
Researcher 5 11%
Student > Master 4 9%
Other 9 20%
Unknown 10 23%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 12 27%
Agricultural and Biological Sciences 9 20%
Medicine and Dentistry 7 16%
Biochemistry, Genetics and Molecular Biology 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 5%
Unknown 11 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2014.
All research outputs
#16,721,717
of 25,374,647 outputs
Outputs from BMC Veterinary Research
#1,360
of 3,298 outputs
Outputs of similar age
#198,846
of 320,940 outputs
Outputs of similar age from BMC Veterinary Research
#27
of 51 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,298 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 53% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,940 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 51 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.