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Leukemia cells induce changes in human bone marrow stromal cells

Overview of attention for article published in Journal of Translational Medicine, December 2013
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About this Attention Score

  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

Mentioned by

twitter
5 tweeters

Citations

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43 Dimensions

Readers on

mendeley
107 Mendeley
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Title
Leukemia cells induce changes in human bone marrow stromal cells
Published in
Journal of Translational Medicine, December 2013
DOI 10.1186/1479-5876-11-298
Pubmed ID
Authors

Sara Civini, Ping Jin, Jiaqiang Ren, Marianna Sabatino, Luciano Castiello, Jianjian Jin, Huan Wang, Yuanlong Zhao, Francesco Marincola, David Stroncek

Abstract

Bone marrow stromal cells (BMSCs) are multipotent cells that support angiogenesis, wound healing, and immunomodulation. In the hematopoietic niche, they nurture hematopoietic cells, leukemia, tumors and metastasis. BMSCs secrete of a wide range of cytokines, growth factors and matrix proteins which contribute to the pro-tumorigenic marrow microenvironment. The inflammatory cytokines IFN-γ and TNF-α change the BMSC secretome and we hypothesized that factors produced by tumors or leukemia would also affect the BMSC secretome and investigated the interaction of leukemia cells with BMSCs.

Twitter Demographics

The data shown below were collected from the profiles of 5 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 107 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 <1%
Turkey 1 <1%
India 1 <1%
Unknown 104 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 30%
Researcher 18 17%
Student > Master 16 15%
Student > Bachelor 12 11%
Student > Doctoral Student 5 5%
Other 14 13%
Unknown 10 9%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 33 31%
Agricultural and Biological Sciences 32 30%
Medicine and Dentistry 17 16%
Engineering 4 4%
Nursing and Health Professions 2 2%
Other 4 4%
Unknown 15 14%

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 December 2013.
All research outputs
#13,048,906
of 22,733,113 outputs
Outputs from Journal of Translational Medicine
#1,510
of 3,974 outputs
Outputs of similar age
#161,811
of 306,889 outputs
Outputs of similar age from Journal of Translational Medicine
#53
of 116 outputs
Altmetric has tracked 22,733,113 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,974 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,889 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 116 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.