BRCA1 promoter hypermethylation, 53BP1 protein expression and PARP-1 activity as biomarkers of DNA repair deficit in breast cancer

Overview of attention for article published in BMC Cancer, November 2013

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Background: Poly(adenosine diphosphate--ribose) polymerase 1 (PARP-1) and the balance between BRCA1 and 53BP1 play a key role…

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