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Multicolor banding remains an important adjunct to array CGH and conventional karyotyping

Overview of attention for article published in Molecular Cytogenetics, December 2013
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Title
Multicolor banding remains an important adjunct to array CGH and conventional karyotyping
Published in
Molecular Cytogenetics, December 2013
DOI 10.1186/1755-8166-6-55
Pubmed ID
Authors

Susan M Bint, Angela F Davies, Caroline Mackie Ogilvie

Abstract

Array comparative genomic hybridization (CGH) for high resolution detection of chromosome imbalance, and karyotype analysis using G-banded chromosomes for detection of chromosome rearrangements, provide a powerful diagnostic armoury for clinical cytogenetics. However, abnormalities detected by karyotype analysis cannot always be characterised by scrutinising the G-banded pattern alone, and imbalance detected by array CGH cannot always be visualised in the context of metaphase chromosomes. In some cases further techniques are needed for detailed characterisation of chromosomal abnormalities. We investigated seven cases involving structural chromosome rearrangements detected by karyotype analysis, and one case where imbalance was primarily detected by array CGH. Multicolor banding (MCB) was used in all cases and proved invaluable in understanding the detailed structure of the abnormalities.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 8 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 8 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 1 13%
Student > Bachelor 1 13%
Researcher 1 13%
Unknown 5 63%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 1 13%
Agricultural and Biological Sciences 1 13%
Medicine and Dentistry 1 13%
Unknown 5 63%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2013.
All research outputs
#17,286,379
of 25,374,917 outputs
Outputs from Molecular Cytogenetics
#166
of 423 outputs
Outputs of similar age
#204,751
of 320,227 outputs
Outputs of similar age from Molecular Cytogenetics
#8
of 18 outputs
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So far Altmetric has tracked 423 research outputs from this source. They receive a mean Attention Score of 2.4. This one is in the 46th percentile – i.e., 46% of its peers scored the same or lower than it.
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We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.