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Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy: study protocol of a cluster randomized clinical trial (Multi-PAP project…

Overview of attention for article published in Implementation Science, April 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (77th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

Mentioned by

twitter
15 tweeters

Citations

dimensions_citation
28 Dimensions

Readers on

mendeley
192 Mendeley
citeulike
1 CiteULike
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Title
Effectiveness of an intervention for improving drug prescription in primary care patients with multimorbidity and polypharmacy: study protocol of a cluster randomized clinical trial (Multi-PAP project)
Published in
Implementation Science, April 2017
DOI 10.1186/s13012-017-0584-x
Pubmed ID
Authors

Prados-Torres, Alexandra, del Cura-González, Isabel, Prados-Torres, Daniel, López-Rodríguez, Juan A., Leiva-Fernández, Francisca, Calderón-Larrañaga, Amaia, López-Verde, Fernando, Gimeno-Feliu, Luis A., Escortell-Mayor, Esperanza, Pico-Soler, Victoria, Sanz-Cuesta, Teresa, Bujalance-Zafra, Mª Josefa, Morey-Montalvo, Mariel, Boxó-Cifuentes, José Ramón, Poblador-Plou, Beatriz, Fernández-Arquero, José Manuel, González-Rubio, Francisca, Ramiro-González, María D., Coscollar-Santaliestra, Carlos, Martín-Fernández, Jesús, Barnestein-Fonseca, Mª Pilar, Valderas-Martínez, José María, Marengoni, Alessandra, Muth, Christiane

Abstract

Multimorbidity is associated with negative effects both on people's health and on healthcare systems. A key problem linked to multimorbidity is polypharmacy, which in turn is associated with increased risk of partly preventable adverse effects, including mortality. The Ariadne principles describe a model of care based on a thorough assessment of diseases, treatments (and potential interactions), clinical status, context and preferences of patients with multimorbidity, with the aim of prioritizing and sharing realistic treatment goals that guide an individualized management. The aim of this study is to evaluate the effectiveness of a complex intervention that implements the Ariadne principles in a population of young-old patients with multimorbidity and polypharmacy. The intervention seeks to improve the appropriateness of prescribing in primary care (PC), as measured by the medication appropriateness index (MAI) score at 6 and 12 months, as compared with usual care. Design: pragmatic cluster randomized clinical trial. Unit of randomization: family physician (FP). Unit of analysis: patient. PC health centres in three autonomous communities: Aragon, Madrid, and Andalusia (Spain). patients aged 65-74 years with multimorbidity (≥3 chronic diseases) and polypharmacy (≥5 drugs prescribed in ≥3 months). n = 400 (200 per study arm). complex intervention based on the implementation of the Ariadne principles with two components: (1) FP training and (2) FP-patient interview. MAI score, health services use, quality of life (Euroqol 5D-5L), pharmacotherapy and adherence to treatment (Morisky-Green, Haynes-Sackett), and clinical and socio-demographic variables. primary outcome is the difference in MAI score between T0 and T1 and corresponding 95% confidence interval. Adjustment for confounding factors will be performed by multilevel analysis. All analyses will be carried out in accordance with the intention-to-treat principle. It is essential to provide evidence concerning interventions on PC patients with polypharmacy and multimorbidity, conducted in the context of routine clinical practice, and involving young-old patients with significant potential for preventing negative health outcomes. Clinicaltrials.gov, NCT02866799.

Twitter Demographics

The data shown below were collected from the profiles of 15 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 192 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 <1%
Unknown 191 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 33 17%
Student > Bachelor 24 13%
Student > Master 20 10%
Other 15 8%
Student > Ph. D. Student 15 8%
Other 38 20%
Unknown 47 24%
Readers by discipline Count As %
Medicine and Dentistry 69 36%
Nursing and Health Professions 22 11%
Pharmacology, Toxicology and Pharmaceutical Science 13 7%
Psychology 11 6%
Computer Science 4 2%
Other 16 8%
Unknown 57 30%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 April 2018.
All research outputs
#2,207,193
of 13,793,900 outputs
Outputs from Implementation Science
#622
of 1,401 outputs
Outputs of similar age
#58,661
of 263,841 outputs
Outputs of similar age from Implementation Science
#7
of 15 outputs
Altmetric has tracked 13,793,900 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,401 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.4. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,841 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 77% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.