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Mendeley readers
Title |
Synthesis and biological evaluation of Combretastatin A-4 derivatives containing a 3’-O-substituted carbonic ether moiety as potential antitumor agents
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Published in |
BMC Chemistry, December 2013
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DOI | 10.1186/1752-153x-7-179 |
Pubmed ID | |
Authors |
Mingyi Ma, Longru Sun, Hongxiang Lou, Mei Ji |
Abstract |
Combretastatin A-4 (CA-4), which is an excellent antineoplastic agent, was isolated from Combretum caffrum. To date, structural modification studies of CA-4 have focused predominantly on the construction of new therapeutic agents for drug discovery. As a part of our ongoing work towards the modification of natural products, we have focused on the 3'-O-substituent groups in the B-ring of CA-4 under the hypothesis that these novel derivatives will possess good bioactivities and behave as effective antiproliferative pro-drugs. |
Mendeley readers
The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
India | 1 | 3% |
Unknown | 37 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 7 | 18% |
Student > Master | 5 | 13% |
Student > Bachelor | 4 | 10% |
Student > Ph. D. Student | 4 | 10% |
Professor | 2 | 5% |
Other | 6 | 15% |
Unknown | 11 | 28% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 18 | 46% |
Agricultural and Biological Sciences | 3 | 8% |
Biochemistry, Genetics and Molecular Biology | 2 | 5% |
Social Sciences | 2 | 5% |
Medicine and Dentistry | 1 | 3% |
Other | 1 | 3% |
Unknown | 12 | 31% |