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The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways

Overview of attention for article published in Molecular Pain, December 2013
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Title
The mTOR signaling pathway regulates pain-related synaptic plasticity in rat entorhinal-hippocampal pathways
Published in
Molecular Pain, December 2013
DOI 10.1186/1744-8069-9-64
Pubmed ID
Authors

Dan Lyu, Wenli Yu, Ning Tang, Ruirui Wang, Zhenyu Zhao, Fang Xie, Yongjin He, Hongyin Du, Jun Chen

Abstract

Our previous work demonstrated that persistent peripheral nociception (PPN) leads to synaptic plasticity and functional changes in the rat hippocampus. The protein kinase mTOR is a critical regulator of protein synthesis-dependent synaptic plasticity in the hippocampus as well as synaptic plasticity associated with central and peripheral pain sensitization. We examined the role of mTOR signaling in pain-associated entorhinal cortex (EC) - hippocampal synaptic plasticity to reveal possible cellular mechanisms underlying the effects of chronic pain on cognition and emotion.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 43 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Chile 2 5%
Japan 1 2%
United Kingdom 1 2%
Sweden 1 2%
Unknown 38 88%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 19%
Student > Master 8 19%
Student > Bachelor 6 14%
Professor 3 7%
Professor > Associate Professor 3 7%
Other 8 19%
Unknown 7 16%
Readers by discipline Count As %
Medicine and Dentistry 10 23%
Neuroscience 8 19%
Agricultural and Biological Sciences 5 12%
Engineering 3 7%
Psychology 3 7%
Other 4 9%
Unknown 10 23%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2013.
All research outputs
#20,655,488
of 25,373,627 outputs
Outputs from Molecular Pain
#477
of 669 outputs
Outputs of similar age
#244,809
of 320,279 outputs
Outputs of similar age from Molecular Pain
#35
of 58 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,279 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 58 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.